The SLC29A1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ENT1, and SLC29A1. This antibody recognizes Human antigen. The SLC29A1 Antibody has been validated for the following applications: ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
SLC29A1 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A1 is a transmembrane glycoprotein that localizes to the plasma and mitochondrial membranes and mediates the cellular uptake of nucleosides from the surrounding medium (3). As a nucleoside transporter, SLC29A1 plays an important role in the uptake of nucleoside-based anti-cancer drugs; polymorphisms of point mutations in the gene encoding this protein may affect the efficacy of these drugs (4)